Remember that your diabetic foot sore (or diabetic foot ulcer) will not heal overnight. But it is important that you do all you can to make sure your diabetic foot sore heals properly. That is because a diabetic foot sore that doesn’t heal can lead to further complications such as infection, hospitalization, or amputation.

Your first step in healing a diabetic foot sore is practicing good wound care. Partner with your doctor or wound care specialist to treat your diabetic foot sore in its early stages.

Good wound care involves:


Your doctor will remove any dead tissue around the sore, because unhealthy tissue prevents healing.

Infection control

Antibiotics may be prescribed to help fight infection.


Pressure is taken off the sore with a special boot, crutches, cast, or therapeutic footwear to give the sore a chance to heal.

When good wound care isn’t enough

Even when you and your doctor properly care for a diabetic foot sore, it still may not heal. If your doctor is not happy with the healing of your wound, another treatment regimen will be considered. At this time, your doctor may prescribe treatment with REGRANEX Gel.

Tips to stay on track

A diabetic foot sore does not heal overnight. That is why it is very important to stay on track with treatment.

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Diabetes and foot wound problems

The effects of diabetes can slow wound healing anywhere on the body. Small cuts and blisters can easily develop into deep sores.

Learn about diabetic foot sores
Preventing diabetic foot sores

Prevention is the key to keeping healthy feet and reducing the likelihood of diabetic foot ulcers.

Learn about prevention
Important Safety Information

People who use 3 or more tubes of REGRANEX (becaplermin) Gel may have an increased risk of death from cancer.

REGRANEX Gel is a man-made protein medicine that is used with other ulcer care practices (such as good wound care) to treat diabetic sores (ulcers) of your legs or feet that are deeper than just your skin, in people who have good blood supply to the legs.

Do not use REGRANEX Gel if you have a skin tumor at the area where you apply the product.

Before you use REGRANEX Gel, tell your healthcare provider if you:

If you decide to use REGRANEX Gel, use the product exactly as your healthcare provider tells you to use it. This includes following your healthcare provider's instructions about not putting weight on the affected leg and foot (non-weight bearing).

Keep REGRANEX Gel and all medicines out of the reach of children. Do not use REGRANEX Gel for a condition for which it was not prescribed. Do not give REGRANEX Gel to other people, even if they have the same symptoms that you have. It may harm them.

Read the Medication Guide before you start using REGRANEX Gel and each time you get a refill. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment.

Important Safety Information


An increased rate of mortality secondary to malignancy was observed in patients treated with 3 or more tubes of REGRANEX (becaplermin) Gel, 0.01% in a postmarketing retrospective cohort study. REGRANEX Gel should only be used when the benefits can be expected to outweigh the risks. REGRANEX Gel should be used with caution in patients with known malignancy.

Important Safety Information

People who use 3 or more tubes of REGRANEX (becaplermin) Gel may have an increased risk of death from cancer.

You should talk with your healthcare provider about the possible benefits and risks to you if you use more than 3 tubes of REGRANEX Gel. If you already have cancer, you and your healthcare provider should carefully consider whether you will use REGRANEX Gel.