Prevention is the key to keeping healthy feet. Control your blood sugar and practice good foot hygiene by taking care of your feet every day, wearing proper footwear, avoiding foot injury, and scheduling regular checkups with your doctor.

Control blood sugar levels

  • Eat healthy meals: Well-balanced meals with the right mix of starches, fruits and vegetables, proteins, and fats are especially important. Blood sugar levels are highest an hour or two after you eat
  • Exercise daily: Muscles use sugar for energy, and exercise improves your body’s response to insulin
  • Coordinate your medication with your meals, because too much or too little food in relation to your insulin medication may affect your blood sugar levels

Make foot care a part of your routine

Get checkups

  • Have your feet checked regularly by your doctor or podiatrist
  • Never skip a doctor’s appointment
  • Don’t remove corns or calluses by yourself. See your doctor for assistance


  • Wash with a mild soap and water
  • Dry well between your toes
  • Apply lotion to the bottom of your feet (not between your toes)
  • Trim toenails regularly


  • Check for cuts, cracks, blisters, scratches, red spots, or swelling
  • If you cannot see the bottom of your feet, use a hand mirror
  • Call your doctor right away if you think you have a foot sore
  • Call your doctor right away if you have any signs of infection, including redness, swelling, drainage, fever, or pain


  • Wear clean socks
  • Wear proper fitting shoes (avoid high heels, tight shoes, and shoes without toe and heel protection, like sandals)
  • Avoid injury to your feet — avoid sun exposure, check the insides of your shoes before putting them on, and don't go barefoot
Practicing good wound care

Unhealed foot sores can lead to further complications. Timely treatment and good wound care is essential.

Learn about treatment
Diabetes and wound problems

The effects of diabetes can slow wound healing anywhere on the body. Small cuts and blisters can easily develop into deep sores.

Learn about diabetic foot sores
Important Safety Information

People who use 3 or more tubes of REGRANEX (becaplermin) Gel may have an increased risk of death from cancer.

REGRANEX Gel is a man-made protein medicine that is used with other ulcer care practices (such as good wound care) to treat diabetic sores (ulcers) of your legs or feet that are deeper than just your skin, in people who have good blood supply to the legs.

Do not use REGRANEX Gel if you have a skin tumor at the area where you apply the product.

Before you use REGRANEX Gel, tell your healthcare provider if you:

If you decide to use REGRANEX Gel, use the product exactly as your healthcare provider tells you to use it. This includes following your healthcare provider's instructions about not putting weight on the affected leg and foot (non-weight bearing).

Keep REGRANEX Gel and all medicines out of the reach of children. Do not use REGRANEX Gel for a condition for which it was not prescribed. Do not give REGRANEX Gel to other people, even if they have the same symptoms that you have. It may harm them.

Read the Medication Guide before you start using REGRANEX Gel and each time you get a refill. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment.

Important Safety Information


An increased rate of mortality secondary to malignancy was observed in patients treated with 3 or more tubes of REGRANEX (becaplermin) Gel, 0.01% in a postmarketing retrospective cohort study. REGRANEX Gel should only be used when the benefits can be expected to outweigh the risks. REGRANEX Gel should be used with caution in patients with known malignancy.

Important Safety Information

People who use 3 or more tubes of REGRANEX (becaplermin) Gel may have an increased risk of death from cancer.

You should talk with your healthcare provider about the possible benefits and risks to you if you use more than 3 tubes of REGRANEX Gel. If you already have cancer, you and your healthcare provider should carefully consider whether you will use REGRANEX Gel.